Prof. Dr. MEHMET BOYRAZ

Medical Interests: Growth and developmental delays
Malnutrition
Short stature
Loss of appetite
Early puberty
Delayed puberty
Diabetes (diabetes mellitus)
Obesity
Goiter
Thyroid gland diseases
Hypothyroidism
Hyperthyroidism
Hashimoto's disease
Adrenal gland disease
Adrenal hyperplasia (congenital)
Adrenal insufficiency
Cushing syndrome
Excessive hair growth
Menstrual irregularity
Polycystic ovary disease
Turner syndrome
Penile problems (small penis)
Calcium metabolism disorders
Bone diseases
Pituitary diseases
Disorders of sex development
Micropenis
Undescended testis
Ambiguous genital structure
Rickets
Congenital thyroid diseases

A1. Yeşilkaya E, Cinaz P, Bideci A, Camurdan O, Boyraz M. A 46XX disorder of sex development with a prostate gland and increased level of prostate-specific antigen. J Natl Med Assoc. 2008;100(2):256-258 (Science Citation Index Expanded).

A2. Yeşilkaya E, Koç A, Bideci A, Camurdan O, Boyraz M, Erkal O, Ergun MA, Cinaz P. CTLA4 gene polymorphisms in children and adolescents with autoimmune thyroid diseases. Genet Test. 2008;12(3):461-464 (Science Citation Index Expanded).

A3. Yeşilkaya E, Bideci A, Ozer C, Elmas C, Camurdan O, Giray SG, Boyraz M, Vurucu S, Cinaz P. Plant growth regulator (4-chlorophenoxy acetic acid) increases apoptosis in gonads of rats without changing hormonal levels. Horm Res. 2009;72(4):225-235 (Science Citation Index).

A4. Yeşilkaya E, Bideci A, Çamurdan O, Boyraz M, Vurucu S, Cinaz P. Association of osteoprotegerin and rankl levels with insulin resistance in pubertal obese children. Central European Journal of Medicine. 2010;5(2):261-267 (Science Citation Index Expanded).

A5. Emeksiz H, Bakkaloglu S, Camurdan O, Boyraz M, Soylemezoglu O, Hasanoglu E, Buyan N. Acute adrenal crisis mimicking familial Mediterranean fever attack in a renal transplant FMF patient with amyloid goiter. Rheumatol Int. 2010;30(12):1647-1649 (Science Citation Index).

A6. Taşçılar ME, Yokuşoğlu M, Boyraz M, Baysan O, Köz C, Dündaröz R. Cardiac autonomic functions in obese children. J Clin Res Pediatr Endocrinol. 2011;3(2):60-64 (PubMed).

A7. Cinaz P, Yeşilkaya E, Onganlar YH, Boyraz M, Bideci A, Camurdan O, Karaoğlu AB. Penile anthropometry of normal prepubertal boys in Turkey. Acta Paediatr. 2012;101(1):33-36 (Science Citation Index).

A8. Ozgen IT, Tascilar ME, Bilir P, Boyraz M, Guncikan MN, Akay C, Dundaroz R. Oxidative stress in obese children and its relation with insulin resistance. J Pediatr Endocrinol Metab. 2012;25(3-4):261-266 (Science Citation Index).

A9. Boyraz M, Bideci A, Karaoğlu A, Hatipoğlu N. Idiopathic menarche presenting at nine months of age: A case report. HealthMED. 2013; 7(3): 976-979 ((Electronic Social and Science Citation Index (ESSCI)).

A10. Boyraz M, Cekmez F, Karaoğlu A, Cinaz P, Durak M, Bideci A. Relationship of adipokines (adiponectin, resistin and RBP4) with metabolic syndrome components in pubertal obese children. Biomark Med. 2013;7(3):423-428 (Science Citation Index Expanded).

A11. Boyraz M, Ulucan K, Taşkın N, Akçay T, Flanagan SE, Mackay DJ. Transient neonatal diabetes mellitus in a Turkish patient with three novel homozygous variants in the ZFP57 gene. J Clin Res Pediatr Endocrinol. 2013;5(2):125-128 (PubMed).

A12. Akcay A, Ulucan K, Taskin N, Boyraz M, Akcay T, Zurita O, Gomez A, Heath KE, Campos-Barros A. Suprasellar mass mimicking a hypothalamic glioma in a patient with a complete PROP1 deletion. Eur J Med Genet. 2013;56(8):445-451 (Science Citation Index).

A13. Boyraz M, Cekmez F, Karaoglu A, Cinaz P, Durak M, Bideci A. Serum adiponectin, leptin, resistin and RBP4 levels in obese and metabolic syndrome children with nonalcoholic fatty liver disease. Biomark Med. 2013;7(5):737-745 (Science Citation Index Expanded).

A14. Bitkin EC, Boyraz M, Taşkın N, Akçay A, Ulucan K, Akyol MB, Akçay T. Effects of ACE Inhibitors on Insulin Resistance and Lipid Profile in Children with Metabolic Syndrome. J Clin Res Pediatr Endocrinol. 2013;10(3):164-169 (PubMed).

A15. Boyraz M, Pirgon O, Akyol B, Dündar B, Cekmez F, Eren N. Importance of epicardial adipose tissue thickness measurement in obese adolescents, its relationship with carotid intima-media thickness, and echocardiographic findings. European Review for Medical and Pharmacological Sciences. 2013;17(24): 3309-3317. (Science Citation Index Expanded)

A16. Boyraz M, Hatipoğlu N, Sarı E, Akçay A, Taşkın N, Ulucan K, Akçay T. Non-alcoholic fatty liver disease in obese children and the relationship between metabolic syndrome criteria. Obesity Research & Clinical Practice 2013 http://dx.doi.org/10.1016/j.orcp.2013.08.003 (Science Citation Index Expanded).

B. Papers presented at international scientific meetings and published in proceedings books (Proceedings):

B1. Yesilkaya E, Bideci, A Ozer C, Boyraz M. Hormonal and histopathologic evaluation of the effects of plant growth regulator, 4-cholorophenoxy acetic acid, on the gonadal functions of rats. Hormn Res 2008;70(suppl 1):21. 47 th Annual Meeting of the European Society for Paediatric Endocrinology, İstanbul, Turkey.

B2. Yesilkaya E, Bideci A, Camurdan O, Boyraz M, Cinaz, P. Association of osteoprotegerin and RANKL levels with insulin resistance in pubertal obese children. Hormn Res 2008;70(suppl 1):125. 47 th Annual Meeting of the European Society for Paediatric Endocrinology, İstanbul, Turkey.

B3. Yesilkaya E, Bideci A, Ergun MA, Koc A, Camurdan MO, Boyraz M, Erkal O, Cinaz P. Investigation of CTLA4 gene polymorphisms in children and adolescents with autoimmune Thyroid disease. Hormn Res 2008;70(suppl 1):166. 47 th Annual Meeting of the European Society for Paediatric Endocrinology, İstanbul, Turkey.

B4. Cinaz P, Boyraz M, Yesilkaya E, Ezgü F, Bideci A, Çamurdan O. SOCS-3 gene polymorphisms in obesity and metabolic syndrome. Hormn Res Paediatr 2010; 74(suppl 3):127. 49 th Annual Meeting of the European Society for Paediatric Endocrinology, Prague, Czech Republic.

B5. Emeksiz H, Bakkaloglu S, Camurdan O, Boyraz M, Soylemezoglu O, Hasanoglu E, Buyan N. Acute adrenal crisis mimicking familial Mediterranean fever attack in a renal transplant FMF patient with amyloid goiter: Acase report. Hormn Res Paediatr 2010; 74(suppl 3):261. 49 th Annual Meeting of the European Society for Paediatric Endocrinology, Prague, Czech Republic.

B6. Hatipoglu N, Kurtoglu S, Mazicioglu MM, Boyraz M. Gul A. Neck circumference as a novel parameter to determine non-alcoholic fatty liver disease in obese children. Horm Res 2011;76(suppl 2):77. 50 th Annual Meeting of the European Society for Paediatric Endocrinology, Glasgow, Scotland.

B7. Özgen IT, Tascilar ME, Bilir P, Boyraz M, Guncikan MN, Akay C. Evaluation of oxidative stress in obese children. Horm Res 2011;76(suppl 2):78. 50 th Annual Meeting of the European Society for Paediatric Endocrinology, Glasgow, Scotland.

B8. Hatipoglu N, Kurtoglu S, Mazicioglu MM, Boyraz M, Gul A. Prevalence of non-alcoholic fatty liver disease in obese children according to gender and pubertal development. Horm Res 2011;76(suppl 2):178. 50 th Annual Meeting of the European Society for Paediatric Endocrinology, Glasgow, Scotland.

B9. Telhan L, Hatipoglu N, Boyraz M, Kılıçaslan Ö, Girgin D. Myxedematous coma due to secondary hypothyroidism with panhypopituitarism. Horm Res 2011;76(suppl 2): 320. 50 th Annual Meeting of the European Society for Paediatric Endocrinology, Glasgow, Scotland.

B10. Boyraz M, Karaoglu B, Sari E, Hatipoglu N, Aysun Bideci A, Cinaz P. Serum concentration of adiponectin, resistin, retinol binding protein 4 and leptin in obese children with non-alcoholic fatty liver disease. Horm Res 2012;78(suppl 1):176. 51 th Annual Meeting of the European Society for Paediatric Endocrinology, Leipzig, Germany.

B11. Hatipoglu N, Kurtoglu S, Mazicioglu MM, Boyraz M. The relationship between changes in anthropometric parameters and cardio-metabolic risk factors. Horm Res 2012;78(suppl 1):184. 51 th Annual Meeting of the European Society for Paediatric Endocrinology, Leipzig, Germany.

B12. Hatipoglu N, Kurtoglu S, Mazicioglu MM, Boyraz M. A new association: normocalcemic hyperparathyroidism and ectodermal dysplasia. Horm Res 2012;78(suppl 1): 260. 51 th Annual Meeting of the European Society for Paediatric Endocrinology, Leipzig, Germany.

B13. Boyraz N, Cinaz P, Karaoğlu AB, Taşçılar E, Bideci A, Çamurdan O, Emeksiz HC. Prevalence of metabolic syndrome, frequency of cardiovascular risk factors and association of leptin level with metabolic syndrome and cardiovascular risk factors in Turkish obese children and adolescents. Horm Res 2012;78(suppl 1):281. 51 th Annual Meeting of the European Society for Paediatric Endocrinology, Leipzig, Germany.

B14. Boyraz M, Karaoğlu A, Bideci A, Cinaz P, Hatipoğlu N. Relationship of adipokines with metabolic syndrome components in pubertal obese children. Horm Res 2012;78(suppl 1): 281-282. 51 th Annual Meeting of the European Society for Paediatric Endocrinology, Leipzig, Germany.

B15. Ulucan K, Akcay T, Bitkin EC, Boyraz M, Taskin N, Kızılocak H, Akcay A. ACE inhibitors have positive effects on insulin resistance and lipid profile in children with metabolic syndrome. Horm Res 2013;80(suppl 1):244 9th Joint Meeting of Paediatric Endocrinology. 19-22 September, 2013 Milan, Italy.

B16. Akcay T, Boyraz M, Ulucan K, Kızılok H, Flanagan SE, Mackay D. Transient neonatal diabetes mellitus in a Turkish patient with three novel homozygous variants in the ZFP57 gene. Horm Res 2013;80(suppl 1):269. 9th Joint Meeting of Paediatric Endocrinology. 19-22 September, 2013 Milan, Italy.

B17. Boyraz M, Ulucan K, Akcay T, Akcay A, Taskin N. SRD5A2 gene mutation can lead to sex development disorder; a case of a Turkish patient with 46,XY. Horm Res 2013;80(suppl 1):347. 9th Joint Meeting of Paediatric Endocrinology. 19-22 September, 2013 Milan, Italy.

B18. Boyraz M, Pirgon O. Interrelations between serum N-terminal pro B-type natriuretic peptide (NT-proBNP) levels and early cardiovascular risk factors and echocardiographic parameters in obese adolescents. Horm Res 2013;80(suppl 1):450. 9th Joint Meeting of Paediatric Endocrinology. 19-22 September, 2013 Milan, Italy.

B19. Boyraz M, Pirgon O, Dundar B, Cekmez F, Akcam M. Long-term treatment of n-3 polyunsaturated fatty acids in obese children with non-alcoholic fatty liver disease. 9th Joint Meeting of Paediatric Endocrinology. 19-22 September, 2013 Milan, Italy.

C. Authored national / international books:

C1. Akçay T, Boyraz M, Mutlu S, Güler O, Mutlu H. Management of Pathological Fractures in Children. pp. 269-291 (Editor: Prof. Dr. Selim Kurtoğlu). Çocuklarda Acil Endokrin Hastalıklar, 2013. Nobel Tıp Kitabevi 2013.

D. Articles published in national peer-reviewed journals:

D1. Yeşilkaya E, Şahbaz H, Boyraz M, Bideci A, Koç A, Cinaz P. Central Precocious Puberty in a Girl with Sturge-Weber Syndrome. Sted. 2008;17(2):23-25.

D2. Yeşilkaya E, Belen B, Bideci A, Çamurdan O, Boyraz M, Cinaz P. Clinical characteristics of children and adolescents with chronic autoimmune thyroiditis. Gülhane Tıp Dergisi 2008;50:147-150.

D3. Boyraz M. To Which Gender Should External Genitalia be Corrected in a Lately Diagnosed 46,XX Congenital Adrenal Hyperplasia Case with Severe Virilization: Case Report. Turkiye Klinikleri J Endocrin 2013;8(1):43-46.

D4. Boyraz M. The relationship between obesity and thyroid function tests in children. Yeni Tıp Dergisi 2013;30(3):160-163.

D5. Boyraz M. Langerhans cell histiocytosis with central nervous system involvement and Rathke's cleft cyst: a case report. Yeni Tıp Dergisi 2013;30(3):204-206.

D6. Boyraz M, Cinaz P, Karaoğlu A, Taşçılar E, Bideci A, Emeksiz HC, Çamurdan O. The Prevalence of Metabolic Syndrome and Its Relation to Leptin Levels in Obese Children and Adolescents. Turkiye Klinikleri J Med Sci 2013;33(4):929-935.

D7. Boyraz M, Dönmez A. A case of type 1 autoimmune polyglandular syndrome presenting with hypercalcemia in childhood. Yeni Tıp Dergisi 2013;30(4):260-262.

E. Papers presented at national scientific meetings and published in proceedings books:

E1. Tayfun M, Boyraz M, Bideci A, Çamurdan O, Cinaz P. A case of panhypopituitarism caused by Langerhans cell histiocytosis limited to the hypothalamic-pituitary axis. 13th National Pediatric Endocrinology and Diabetes Congress, November 2009, Antalya.

E2. Boyraz M, Bideci A, Tayfun M, Çamurdan O, Cinaz P. Idiopathic precocious puberty in infancy: a case report. 13th National Pediatric Endocrinology and Diabetes Congress, November 2009, Antalya.

E3. Boyraz M, Bideci A, Tayfun M, Çamurdan O, Cinaz P. Multiple endocrine organ involvement in a case of primary amyloidosis due to familial Mediterranean fever. 13th National Pediatric Endocrinology and Diabetes Congress, November 2009, Antalya.

E4. Boyraz M, Cinaz P, Bideci A, Yeşilkaya E, Tayfun M, Çamurdan O. SOCS-3 gene polymorphism in children with obesity and metabolic syndrome. 14th National Pediatric Endocrinology and Diabetes Congress, October 2010, Dalaman, Muğla (Oral Presentation).

E5. Hatipoğlu N, Kurtoğlu S, Öz L, Boyraz M. A new parameter in the OGTT: 1-hour blood glucose. 15th National Pediatric Endocrinology and Diabetes Congress, November 2011, Izmir.

E6. Boyraz M, Merve Emecan Şanlı. A case of 46 XX disorder of sexual differentiation due to late-diagnosed congenital adrenal hyperplasia. 15th National Pediatric Endocrinology and Diabetes Congress, November 2011, Izmir.

E7. Boyraz M, Karaoğlu A, Bideci A, Cinaz P, Çamurdan O. Prevalence of metabolic syndrome and frequency of cardiovascular risk factors in Turkish obese children and adolescents. 15th National Pediatric Endocrinology and Diabetes Congress, November 2011, Izmir.

E8. Güleç SG, Hatipoğlu N, Çetinçelik Ü, Boyraz M, Demirci GT, Sakız D. Coincidence of 21-hydroxylase deficiency and epidermolysis bullosa. 15th National Pediatric Endocrinology and Diabetes Congress, November 2011, Izmir.

E9. Hatipoğlu N, Çetinçelik Ü, Demir AA, Güleç SG, Boyraz M, Bülbül A. Canavan disease carrier status in a case of congenital hyperinsulinism. 15th National Pediatric Endocrinology and Diabetes Congress, November 2011, Izmir.

E10. Hatipoğlu N, Kurtoğlu S, Doğan S, Özgen L, Boyraz M. Threshold values of the parameters to be used in demonstrating non-alcoholic fatty liver and their relationship with metabolic syndrome. 15th National Pediatric Endocrinology and Diabetes Congress, November 2011, Izmir (Oral Presentation).

E11. Özgen T, Taşcılar ME, Bilir P, Boyraz M. The relationship between oxidative stress and insulin resistance in obese children. 15th National Pediatric Endocrinology and Diabetes Congress, November 2011, Izmir (Oral Presentation).

E12. Hatipoğlu N, Kurtoğlu S, Öz L, Boyraz M. The role of hepatic enzymes in determining risk in metabolically healthy obese children. 15th National Pediatric Endocrinology and Diabetes Congress, November 2011, Izmir.

E13. Cinaz P, Yeşilkaya E, Onganlar YH, Boyraz M, Bideci A, Karaoğlu B, Emeksiz HC. Penile anthropometry in prepubertal Turkish children. 15th National Pediatric Endocrinology and Diabetes Congress, November 2011, Izmir.

E14. Boyraz M, Akçay T, Bülbül A. Transient neonatal diabetes: a case report. 16th National Pediatric Endocrinology and Diabetes Congress, October 2012, Samsun.

E15. Boyraz M. Cerebral gigantism: on the occasion of a case presenting with a complaint of excessive height. 16th National Pediatric Endocrinology and Diabetes Congress, October 2012, Samsun.

E16. Boyraz M, Taşçılar ME, Cinaz P, Bideci A, Karaoğlu AB, Çamurdan O. Adipokine levels in pubertal obese children and their relationship with metabolic syndrome components. 16th National Pediatric Endocrinology and Diabetes Congress, October 2012, Samsun.

E17. Boyraz M, Halefoğlu A. Langerhans cell histiocytosis limited to the hypothalamo-pituitary axis accompanied by prolactinoma: a case report. 16th National Pediatric Endocrinology and Diabetes Congress, October 2012, Samsun.

E18. Boyraz M. A case of autoimmune polyglandular syndrome (APS) type 1 presenting with hypercalcemia. 16th National Pediatric Endocrinology and Diabetes Congress, October 2012, Samsun.

E19. Boyraz M, Taşçılar ME, Cinaz P, Bideci A, Çamurdan O, Emeksiz HC. The relationship of non-alcoholic fatty liver disease with metabolic syndrome and cardiovascular risk factors in children. 16th National Pediatric Endocrinology and Diabetes Congress, October 2012, Samsun.

E20. Boyraz M, Karaoğlu AB, Cinaz P, Taşçılar ME, Çekmez F, Bideci A, Çamurdan O, Hatipoğlu N. Leptin, adiponectin, resistin and retinol-binding protein 4 levels in obese patients with non-alcoholic fatty liver and metabolic syndrome. 16th National Pediatric Endocrinology and Diabetes Congress, October 2012, Samsun (Oral Presentation).

E21. Boyraz M, Pirgon Ö, Çekmez F. Long-term effects of omega-3 polyunsaturated fatty acids in obese children with non-alcoholic fatty liver disease. 17th National Pediatric Endocrinology and Diabetes Congress, October 2013, Edirne (Oral Presentation).

E22. Boyraz M, Pirgon Ö, Eren N, Akyol B. Relationship of serum N-terminal pro B-type natriuretic peptide (NT-pro-BNP) levels with early cardiovascular disease and cardiac function in obese adolescents. 17th National Pediatric Endocrinology and Diabetes Congress, October 2013, Edirne.

E23. Boyraz M, Akyol B, Pirgon Ö, Dönmez A. Importance of epicardial adipose tissue thickness measurement in obese children and adolescents and its relationship with carotid intima-media thickness and echocardiographic findings. 17th National Pediatric Endocrinology and Diabetes Congress, October 2013, Edirne.

E24. Boyraz M, Dönmez A. The relationship between obesity and thyroid function tests in children. 17th National Pediatric Endocrinology and Diabetes Congress, October 2013, Edirne.

E25. Boyraz M, Akyol B. Myocardial functions in obese children with subclinical hypothyroidism. 17th National Pediatric Endocrinology and Diabetes Congress, October 2013, Edirne.

F. Other publications:

F1. Republic of Turkey Ministry of Health Diagnosis and Treatment Guidelines for Poisonings in Primary Care. Editors: Prof. Dr. Yeşim TUNÇOK, Prof. Dr. Nuri İhsan KALYONCU, Prof. Dr. Ufuk BEYAZOVA, Prof. Dr. Ersin YARIŞ. Republic of Turkey Ministry of Health Refik Saydam Hygiene Center Presidency, School of Hygiene Directorate Publications, Yücel Ofset Printing 2007, Ankara.